112 36γ stimulates tumor-associated macrophages to recruit IL-17 producing cells in cutaneous squamous cell carcinoma
نویسندگان
چکیده
منابع مشابه
The Accumulation and Prognosis Value of Tumor Infiltrating IL-17 Producing Cells in Esophageal Squamous Cell Carcinoma
BACKGROUND The role of IL-17 producing cells in tumors is controversial. In the present study, we investigated the prognostic value of measuring tumor-infiltrating IL-17 producing cell levels in human esophageal squamous cell carcinoma (ESCC). METHODOLOGY/PRINCIPAL FINDINGS Immunohistochemical staining was performed to investigate the levels of IL-17+ tumor infiltrating lymphocytes (TILs), as...
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Background:Squamous cell carcinoma (SCC) is the most common malignancy of the oral cavity, which is highly invasive. Verrucous carcinoma (VC) is the low-grade form of SCC. Epithelial dysplasia (ED) also has a malignant potential. This immunohistochemical (IHC) study aimed to assess angiogenesis and the presence of tumor-associated macrophages (TAMs) in SCC, VC and ED to determi...
متن کاملDensity of mast-cells and Microvessels Density in head and neck cutaneous Squamous Cell Carcinoma
Background and Aim: Cutaneous squamous cell carcinoma (CSCC) is the second most common skin cancer. Mast cells may play a role in tumor progression and metastasis by increasing angiogenesis. The aim of this study was to investigate the role of mast cells by increasing angiogenesis in invasion of head and neck cutaneous squamous cell carcinoma. Materials and Methods: In this cross-sectional stud...
متن کامل[Clear cells in cutaneous squamous cell carcinoma].
INTRODUCTION Although few cases of squamous cell carcinoma (SCC) with clear cells have been published, we believe that these cells are often present in SCC. MATERIAL AND METHODS We studied 249 SCCs, analyzing a number of clinical and histological variables. Various immunohistochemical techniques (immunoperoxidase method) were used to determine whether adnexal differentiation was present. RE...
متن کاملThe Usefulness of CD10 in Distinguishing between Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma
Background & Objectives: CD10 is a cell surface enzyme with metalloendopeptidase activity, also known as Common Acute Lymphoblastic Leukaemia Antigen, which mainly serves as a marker for acute lymphoblastic leukemia (ALL). To date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed CD10 expression in cutaneous epithelial neoplasms. Our goal was to d...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.02.126